동국대학교 WISE캠퍼스 SITEMAP

의학, 의술, 의도를 함양하여 실천하는 지성인 양성!

한의과대학

교수 경력 및 연구업적

박선동 교수님

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학력

  • 1985. 동국대학교 한의과대학 한의학사
  • 1987. 동국대학교 한의과대학 한의학 석사
  • 1992. 동국대학교 한의과대학 한의학 박사

경력

  • 1993~1994. 동국대학교 한의과대학 전임강사
  • 1994~1998. 동국대학교 한의과대학 조교수
  • 1998~2003. 동국대학교 한의과대학 부교수
  • 2003~ 현재 . 동국대학교 한의과대학 교수

수상 및 활동사항

  • 대통령 표창 (2018)
  • 동국대학교 한의과대학 학장 (2013~2015)
  • 건강보험심사평가원 약제급여평가위원회 한약제제소위원회 위원
  • 식품의약품안전처 건강식품심의위원회 위원
  • 보건복지부 한의약육성발전계획 위원회 위원
  • 대한한의학방제학회 이사

연구업적

  • Polygonum aviculare L. extract reduces fatigue by inhibiting neuroinflammation in restraint-stressed mice. Phytomedicine. 2018.
  • Akebia quinata Decaisne aqueous extract acts as a novel anti fatigue agent in mice exposed to chronic restraint stress. Journal of Ethnopharmacology. 2018.
  • Antioxidant and anti-inflammatory effects of herbal formula SC-E3 in lipopolysaccharide stimulated RAW264.7 macropharges. Evidence-Based Complementary and Alternative Medicine. 2017.
  • Herbal formula SC-E1 supresses lipopolysaccharide-stimulated inflammatory responses through activation of Nrf/HO-1 signaling pathway in RAW264.7 macrophages. BMC Complementary and Alternative Medicine. 2017.
  • Saeng-Kankunbi-Tang ( 生肝健脾汤 ) protects liver against oxidative damage through activation of ERK/Nrf2 pathway. Chinese Journal of Integrative Medicine. 2017.

김영우 교수님

경력 및 활동사항

  • 식품의약품안전처 한약정책과 과장 ( 서기관 )
  • 대한한의학방제학회지 편집위원장
  • 대한 약학회 학술상 (2011)
  • ISO TC 215, TC 249 국가 기술 표준 전문위원 (EMR/ 의료정보 / 한의약품)
  • 한국의약품안전관리원 의약품부작용피해구제위원회 위원

EDUCATION & EXPERIENCE

  • Ph.D. College of Pharmacy, Seoul National University (Molecular Pharmacology)
  • Ph.D. College of Korean Medicine, Dongguk University (Herbal Formula)
  • Korea-EU Research Fellowship (Immunology, Virgen Hospital de la Arrixaca, Spain)

RESEARCH INTERESTS & RELATED SKILLS

  • Study of biomarkers for diagnosis of the disease in Korean Medicine
  • Optimization of herbal formula and herbal pharmaceutics for the treatment of chronic disease
  • Identification of molecular targets (i.e. hepatitis, ASH, NASH, NAFLD) by generation of liver diseases animal models (i.e. fibrosis and cancer) and metabolic diseases models (i.e. high-fat diet, Lieber-De Carli diet, ob/ob , db/db mice)

연구업적

  • Lee EH, Park KI, Kim YW*. Liquiritigenin inhibits hepatic fibrogenesis and TGF- β 1/Smad with Hippo/YAP signal. Phytomedicine. 2019;62
  • Kim KY, Lee SG, Kim YW*. Salinomycin ameliorates oxidative hepatic damage through AMP-activated protein kinase, facilitating autophagy. Toxicology and applied pharmacology. 2018;360:141-149.
  • Lee JH, Baek SY, Kim YW*. Oxyresveratrol ameliorates nonalcoholic fatty liver disease by regulating hepatic lipogenesis and fatty acid oxidation through liver kinase B1 and AMP-activated protein kinase. Chem Biol Interact. 2018;289:68-74.
  • Jung EH, Lee JH, Kim SC, Kim YW* AMPK activation by liquiritigenin inhibited oxidative hepatic injury and mitochondrial dysfunction induced by nutrition deprivation as mediated with induction of farnesoid X receptor. Eur J Nutr. 2017;56:635-647.
  • Lee JH, Jung JY, Kim YW*. Combination of honokiol and magnolol inhibits hepatic steatosis through AMPK-SREBP-1   c pathway. Exp Biol Med 2015;240:508-518.

이주희 교수님

경력

  • 2021.09 ~ 현재 동국대학교 한의과대학 부교수
  • 2015.09 ~ 2021.08 동국대학교 한의과대학 조교수
  • 2012.09 ~ 2015.08 대구한의대학교 한의과대학 연구교수
  • 2012.03 ~ 2012.08 인하대학교 의과학연구소 연구교수
  • 2007.02 ~ 2012.02 인하대병원 중개연구센터 연구원

수상 및 학술활동

  • 동국학술연구상 우수상 (2018.09.19.)
  • 산학협력 유공자 경북도지사 표창 (2019.11.07.)
  • 식품의약품안전처 중앙약사심의위원회 전문가 (2018.08.01.~2020.07.31.)
  • 중소기업기술정보진흥원 중소기업기술개발 지원사업 평가위원 (2018.08.09.~현재)
  • 한국연구재단 의약학단 이공분야기초연구사업 평가위원 (2019.04~현재)
  • 대한의생명과학회 상임이사 및 출판부위원장 (2020.01.01.~현재)
  • 대한한의학방제학회지 편집위원 (2022.10.01.~2024.09.30.)

연구업적

  • Ahn JY, Lim DW, Kim JH, Park SY, Park SD, Lee JH (2025) Sinhyotaklisan as a Potential Therapeutic for Psoriasis: Network Pharmacology and Experimental Validation. International Journal of Molecular Sciences 26(11):5082.
  • Kang HJ*, Lee JH*, Jin YX, Myung Y, Jeong JH (2025) Therapeutic effects of 3D bioprinted mesenchymal stem cell-based artificial lymph nodes in lymphedema treatment. International Journal of Bioprinting 11(X): XX-XX. (co-first author)
  • Ahn JY, Lim DW, Park SY, Lee JH (2025) Sinhyotaklisan alleviates inflammation in LPS-activated macrophages by modulating the heme oxygenase pathway. Journal of Ethnopharmacology 344, 119548.
  • Choi SM, Lee JH, Ko S, Hong SS, Jin HE (2024) Mechanism of Action and Pharmacokinetics of Approved Bispecific Antibodies. Biomolecules & therapeutics 32(6):708-722.
  • Park MS, Kim SE, Lee P, Lee JH, Jung KH, Hong SS (2024) Potential role of ANGPTL4 in cancer progression, metastasis, and metabolism: a brief review. BMB Reports 57(8):343-351
  • Kim MR, Kim DI, Park SY, Kang HJ, Park SD, Lee JH (2024) The Protective Role of Magnoliae Flos in Preventing Ovotoxicity and Managing Ovarian Function: An In Vitro and In Vivo Study. International Journal of Molecular Sciences 25(12):6456.
  • Lee JW, Hong SU, Lee JH, Park SY (2024) Estimation of Validity of A-Mode Ultrasound for Measurements of Muscle Thickness and Muscle Quality. Bioengineering 11(2):149.
  • Han SY, Yu JE, You BH, Kim SY, Bae M, Chae HS, Chin YW, Hong SH, Lee JH, Jung SH, Choi YH (2023) No Interference of H9 Extract on Trastuzumab Pharmacokinetics in Their Combinations. International Journal of Molecular Sciences 24(23):16677.
  • Jeon SK, Park SM, Ahn JY, Kim OH, Kim YW, Park KI, Park SD, Lee JH (2023) Anticancer activity of herbal formula Jisilhaebaekgyeji-Tang against human breast cancer cells and its mechanism. Molecular & Cellular Toxicology 19:437–451.
  • Kang HJ, Moon SY, Kim BK, Myung YJ, Lee JH, Jeong JH (2023) Recellularized lymph node scaffolds with human adipose-derived stem cells enhance lymph node regeneration to improve lymphedema. Scientific Reports 13(1):5397.
  • Lee JH, You HJ, Lee TY, Kang HJ (2022) Current Status of Experimental Animal Skin Flap Models: Ischemic Preconditioning and Molecular Factors. International Journal of Molecular Sciences 23(9):5234.
  • Song YR, Jang MH, Jang B, Bae SJ, Bak SB, Lee SM, Yun UJ, Lee JH, Park SM, Jung DH, Sa BS, Song JK, Lee EH, Kim KY, Park KI, Kim YW, Kim SC (2022) Jageum‑Jung, the herbal pharmaceuticals, inhibits the hepatic fibrogenesis as mediated with TGF‑β1/smad signaling. Molecular & Cellular Toxicology 18:243–251.
  • Kim YJ, Park SY, Lee JH (2021) Berteroin ameliorates lipid accumulation through AMPK-mediated regulation of hepatic lipid metabolism and inhibition of adipocyte differentiation. Life Sciences 282:119668
  • Park JY, Kwon YW, Kim SA, Park SD, Kim CH, Kim JH, Lee JH (2021) Polyherbal formula SC-E3 inhibits rheumatoid arthritis activity in a mouse model of type-II collagen-induced arthritis. Journal of Integrative Medicine 19(3):265-273.
  • Kim YJ, Park SY, Koh YJ, Lee JH (2021) Anti-Neuroinflammatory Effects and Mechanism of Action of Fructus ligustri lucidi Extract in BV2 Microglia. Plants (Basel) 10(4):688.
  • Kim SN, Kim DH, Lee HJ, Lim JS, Lee JH, Park SY, Koh YJ (2021) Effects of Ginsenoside Rg3 on Inhibiting Differentiation, Adipogenesis, and ER Stress-Mediated Cell Death in Brown Adipocytes. Evidence-Based Complementary and Alternative Medicine 2021:6668665.
  • Jeon S, Liu QF, Cai H, Jeong HJ, Kim SH, Kim DI, Lee JH (2020) Administration of a herbal formulation enhanced blastocyst implantation via IκB activation in mouse endometrium. Chinese Medicine 15:112.
  • Park MY, Choo YK, Jeon SH, Jang WG, Lee JH, Park JH, Kim CH (2020) Therapeutic anti-psoriatic effects of myeloid-derived suppressor cells in combination with systemic tacrolimus (FK-506) in an imiquimod-induced mouse model of psoriasis. International Immunopharmacology 86:106553.
  • Kim OH*, Lee JH*, Mah S, Park SY, Hong S, Hong SS (2020) HS‑146, a novel phosphoinositide 3‑kinase α inhibitor, induces the apoptosis and inhibits the metastatic ability of human breast cancer cells. International Journal of Oncology 56(6):1509-1520. (co-first author)
  • Jeon SK, Ahn JY, Park SM, Park SD, Lee JH (2020) Antioxidant, anti-inflammatory, antibacterial and ovoprotective effects of mixture of Ulmi cortex and Smilacis rhizoma extracts. Herbal Formula Science 28(1):41-51.
  • Jeon SK, Kim OH, Park SM, Lee JH*, Park SD* (2020) Effects of glucoraphanin in dexamethasone-induced skeletal muscle atrophy in vitro model. Herbal Formula Science 28(1):29-39. (co-corresponding author)
  • Park SM, Jeon SK, Kim OH, Ahn JY, Kim CH, Park SD, Lee JH (2019) Anti-tumor effects of the ethanolic extract of Trichosanthes kirilowii seeds in colorectal cancer. Chinese Medicine 14:43.
  • Lee EH, Park KI, Kim KY, Lee JH, Jang EJ, Ku SK, Kim SC, Suk HY, Park JY, Baek SY, Kim YW (2019) Liquiritigenin inhibits hepatic fibrogenesis and TGF-β1/Smad with Hippo/YAP signal. Phytomedicine 62:152780.
  • Park JY, Park SD, Koh YJ, Kim DI, Lee JH (2019) Aqueous extract of Dipsacus asperoides suppresses lipopolysaccharide-stimulated inflammatory responses by inhibiting the ERK1/2 signaling pathway in RAW 264.7 macrophages. Journal of Ethnopharmacology 231:253-261.
  • Kim CH, Lim CY, Lee JH, Kim KC, Ahn JY, Lee EJ (2019) Human Embryonic Stem Cells-Derived Mesenchymal Stem Cells Reduce the Symptom of Psoriasis in Imiquimod-Induced Skin Model. Tissue Engineering and Regenerative Medicine 16(1):93-102.
  • Kim CH, Yoo JK, Jeon SH, Lim CY, Lee JH, Koo DB, Park MY (2019) Anti-psoriatic effect of myeloid-derived suppressor cells on imiquimod-induced skin inflammation in mice. Scandinavian Journal of Immunology 89(3):e12742.
  • Ko JH*, Lee JH*, Choi B, Park JY, Kwon YW, Jeon S, Park SD, Kim SN (2018) Neuroprotective Effects of Gagam-Sipjeondaebo-Tang, a Novel Herbal Formula, against MPTP-Induced Parkinsonian Mice and MPP+-Induced Cell Death in SH-SY5Y Cells. Evidence-Based Complementary and Alternative Medicine 2018:7816923. (co-first author)
  • Kim KY, Lee SG, Baek SY, Lee EH, Jang EJ, Lee JH, Ahn SC, Chang JH, Oh TW, Kim SH, Ma JY, Kim SC, Park KI, Kim YW (2018) Salinomycin ameliorates oxidative hepatic damage through AMP-activated protein kinase, facilitating autophagy. Toxicology and Applied Pharmacology 360:141-149.
  • Won AN, Kim SA, Ahn JY, Han JH, Kim CH, Lee JH*, Kim DI* (2018) HO-1 Induction by Selaginella tamariscina Extract Inhibits Inflammatory Response in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages. Evidence-Based Complementary and Alternative Medicine 2018:7816923. (co-corresponding author)
  • Koh YJ, Lee JH, Park SY. (2018) Moxibustion-Simulating Bipolar Radiofrequency Suppresses Weight Gain and Induces Adipose Tissue Browning via Activation of UCP1 and FGF21 in a Mouse Model of Diet-Induced Obesity. Evidence-Based Complementary and Alternative Medicine 2018::4737515.
  • Lee JH, Baek SY, Jang EJ, Ku SK, Kim KM, Ki SH, Kim CE, Park KI, Kim SC, Kim YW (2018) Oxyresveratrol ameliorates nonalcoholic fatty liver disease by regulating hepatic lipogenesis and fatty acid oxidation through liver kinase B1 and AMP-activated protein kinase. Chemico-Biological Interactions 289:68-74.
  • Jang EJ, Kim SC, Lee JH, Lee JR, Kim IK, Baek SY, Kim YW (2018) Fucoxanthin, the constituent of Laminaria japonica, triggers AMPK-mediated cytoprotection and autophagy in hepatocytes under oxidative stress. BMC Complementary and Alternative Medicine 18(1):97.
  • Lee SC, Kwon YW, Park JY, Park SY, Lee JH*, Park SD* (2017) Antioxidant and Anti-Inflammatory Effects of Herbal Formula SC-E3 in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages. Evidence-Based Complementary and Alternative Medicine 2017:1725246. (co-corresponding author)
  • Son YH, Jang EJ, Kim YW, Lee JH (2017) Sulforaphane prevents dexamethasone-induced muscle atrophy via regulation of the Akt/Foxo1 axis in C2C12 myotubes. Biomedicine & Pharmacotherapy 95:1486-1492.
  • Lee JH, Son YH, Kwon YW, Park SY, Koo BS, Jung SH (2017) Anticancer Effects of a Korean Herbal Medicine Formula (H9) via AMPK and HER2-PI3K/Akt Signaling in Breast Cancer Cells. Phytotherapy Research 31(11):1765-1775.
  • Park JY, Kwon YW, Lee SC, Park SD, Lee JH (2017) Herbal formula SC-E1 suppresses lipopolysaccharide-stimulated inflammatory responses through activation of Nrf2/HO-1 signaling pathway in Raw 264.7 macrophages. BMC Complementary and Alternative Medicine 17(1):374.
  • Kwon YW, Cheon SY, Park SY, Song J, Lee JH (2017) Tryptanthrin Suppresses the Activation of the LPS-Treated BV2 Microglial Cell Line via Nrf2/HO-1 Antioxidant Signaling. Frontiers in Cellular Neuroscience 11:18.
  • Jung EH, Lee JH, Kim SC, Kim YW (2017) AMPK activation by liquiritigenin inhibited oxidative hepatic injury and mitochondrial dysfunction induced by nutrition deprivation as mediated with induction of farnesoid X receptor. European Journal of Nutrition 56(2):635-647.
  • Seo HL, Baek SY, Lee EH, Lee JH, Lee SG, Kim KY, Jang MH, Park MH, Kim JH, Kim KJ, Lee HS, Ahn SC, Lee JR, Park SJ, Kim SC, Kim YW (2017) Liqustri lucidi Fructus inhibits hepatic injury and functions as an antioxidant by activation of AMP-activated protein kinase in vivo and in vitro. Chemico-Biological Interactions 262:57-68.
  • Kim YW, Jang EJ, Kim CH, Lee JH (2017) Sauchinone exerts anticancer effects by targeting AMPK signaling in hepatocellular carcinoma cells. Chemico-Biological Interactions 261:108-117.
  • Nam EY, Kim SA, Kim HJ, Kim SH, Han JH, Lee JH*, Kim DI* (2016) Akt activation by Evodiae Fructus extract protects ovary against 4-vinylcyclohexene diepoxide-induced ovotoxicity. Journal of Ethnopharmacology 194:733-739. (co-corresponding author)
  • Yoo JK, Choo YK, Kwak DH, Lee JM, Lim CY, Lee JH, Park MY, Kim CH (2016) Protective effects of agonistic anti-4BB antibody on the development of imiquimod-induced psoriasis-like dermatitis in mice. Immunology Letters 178:131-139.
  • Lee IW, Choi HY, Lee JH, Park SD, Kim SM, Ku SK, Zhao RJ, Kim SC, Kim YW, Choi HS (2016) Saeng-Kankunbi-Tang Protects Liver against Oxidative Damage through Activation of ERK/Nrf2 Pathway. Chinese Journal of Integrative Medicine 22(8):619-628.
  • Choi HY*, Lee JH*, Jegal KH, Cho IJ, Kim YW, Kim SC (2016) Oxyresveratrol abrogates oxidative stress as mediated with ERK-Nrf2 pathway in the liver. Chemico-Biological Interactions 245:110-121. (co-first author)
  • Seo HL, Lee JH, Jang MH, Kwon YW, Cho IJ, Kim KJ, Park SJ, Kim SC, Kim YW, Byun SH (2015) Mitochondria protection of Sparganii Rhizoma against oxidative stress in hepatocytes. Herbal Formula Science 23(2):189-198.
  • Lee JH, Park CH, Chun KH, Hong SS (2015) Effects of Adipose-Derived Stem Cell-Conditioned Medium on the Proliferation and Migration of B16 Melanoma Cells. Oncology Letters 10(2):730-736.
  • Lee JH, Jung JY, Jan EJ, Jegal KH, Moon SY, Ku SK, Kang SH, Cho IJ, Park SJ, Lee JR, Zhao RJ, Kim SC, Kim YW (2015) Combination of honokiol and magnolol inhibits hepatic steatosis through AMPK-SREBP-1c pathway. Experimental Biology and Medicine 240(4):508-518.
  • Lee JH, Jang EJ, Seo HL, Ku SK, Lee JR, Shin SS, Park SD, Kim SC, Kim YW (2014) Sauchinone attenuates liver fibrosis and hepatic stellate cell activation through TGF-β/Smad signaling pathway. Chemico-Biological Interactions 224:58-67.
  • Zhao Z, Kim YW, Wu Y, Zhang J, Lee JH, Li X, Cho IJ, Park SM, Jung DH, Yang CH, Kim SC, Zhao R (2014) Korean Red Ginseng attenuates anxiety-like behavior during ethanol withdrawal in rats. Journal of Ginseng Research 38(4):256-263.
  • Lee JH, Jung KH, Lee H, Son MK, Yun SM, Ahn SH, Lee KR, Lee S, Kim D, Hong S, Hong SS (2014) HS-133, a Novel Fluorescent Phosphatidylinositol 3-Kinase Inhibitor, as a Potential Imaging and Anticancer Agent for Targeted therapy. Oncotarget 5(20):10180-10197.
  • Moon SY*, Lee JH*, Choi HY, Cho IJ, Kim SC, Kim YW (2014) Tryptanthrin protects hepatocyte against oxidative stress via activation of the ERK/Nrf2 Pathway. Biological & pharmaceutical bulletin 37(10):1633-1640. (co-first author)
  • Jahn A, Song CK, Balakrishnan P, Hong SS, Lee JH, Chung SJ, Kim DD (2014) AAPE Proliposomes for Topical Atopic Dermatitis Treatment. Journal of Microencapsulation 31(8):768-773.
  • Dong GZ, Lee JH, Ki SH, Yang JH, Cho IJ, Kang SH, Zhao RJ, Kim SC, Kim YW (2014) AMPK activation by isorhamnetin protects hepatocytes against oxidative stress and mitochondrial dysfunction. European Journal of Pharmacology 740:634-340.
  • Hwangbo M, Jung JY, Ki SH, Park SM, Jegal KH, Cho IJ, Lee JH, Kang SH, Park SD, Ku SK, Kim SC, Zhao RJ, Jee SY, Kim YW (2014) U-bang-haequi tang: a herbal prescription that prevents acute inflammation through inhibition of NF-κB-mediated inducible nitric oxide synthase. Evidence-based complementary and alternative medicine 542825:1-12.
  • Yun SM*, Lee JH*, Jung KH, Lee H, Lee S, Hong S, Hong SS (2013) Induction of apoptosis and suppression of angiogenesis of hepatocellular carcinoma by HS-159, a novel phosphatidylinositol 3-kinase inhibitor. International Journal of Oncology 43(1):201-209. (co-first author)
  • Lee JH, Lee H, Yun SM, Jung KH, Jeong Y, Yan HH, Hong S, Hong SS (2013) IPD-196, a novel phosphatidylinositol 3-kinase inhibitor with potent anticancer activity against hepatocellular carcinoma. Cancer Letters 329(1):99-108.
  • Park BH, Jung KH, Son MK, Seo JH, Lee HS, Lee JH, Hong SS (2012) Antitumor activity of Pulsatilla Koreana extract in anaplastic thyroid cancer via apoptosis and anti-angiogenesis. Molecular Medicine Reports 7(1):26-30.
  • Song CK, Lee JH, Jahn A, Choi MJ, Namgoong SK, Hong SS, Chong S, Shim CK, Chung SJ, Kim DD (2012) In vitro and In vivo Evaluation of N,N,N-trimethylphytosphingosine (TMP) and TMP Liposomes for the Treatment of Angiogenesis and Metastasis. International Journal of Pharmaceutics 434(1-2):191-198.
  • Choi MJ*, Lee H*, Lee JH*, Jung KH, Kim D, Hong S, Hong SS (2012) The effect of HS-111, a novel thiazolamine derivative, on apoptosis and angiogenesis of hepatocellular carcinoma cells. Archives of Pharmacal Research 35(4):747-754. (co-first author)
  • Lee H, Lee GY, Jung Y, Jung KH, Lee JH, Ham K, Hong S, Hong SS (2012) A novel imidazopyridine analogue as a phosphatidylinositol 3-kinase inhibitor against human breast cancer. Cancer Letters 318(1):68-75.
  • Lee JH, Lee H, Joung YK, Jung KH, Choi JH, Lee DH, Park KD, Hong SS (2011) The use of low molecular weight heparin-pluronic nanogels impedes liver fibrosis by inhibiting the TGF-β/Smad signaling pathway. Biomaterials 32(5):1438-1445.
  • Lee HS*, Lee JH*, Jung KH, and Hong SS (2010) Deguelin promotes apoptosis and inhibits proliferation of gastric cancer. Oncology Reports 24(4):957-963. (IF = 4.136)
  • Sung JH, Park SH, Seo DW, Lee JH, Hong SW, Hong SS (2009) Antioxidative and skin whitening effect of an aqueous extract of Salicornia herbacea. Bioscience Biotechnology and Biochemistry 73(3):552-556.
  • Lee JH, Lee DH, Lee HS, Choi JS, Kim KW, Hong SS (2008) Deguelin inhibits hepatocellular carcinoma by antiangiogenesis and apoptosis. Oncology Reports 20(1):129-134.
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